The Neuron: Cell and Molecular Biology

 
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The Neuron: Cell and Molecular Biology

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The third edition of The Neuron provides a comprehensive first course in the cell and molecular biology of nerve cells. The first part of the book covers the properties of the many newly discovered ion channels that have emerged through mapping of the genome. These channels shape the way a
single neuron generates varied patterns of electrical activity. Next are covered the molecular mechanisms that convert electrical activity into the secretion of neurotransmitter hormones at synaptic junctions between neurons. The second part of the book covers the biochemical pathways that are
linked to the action of neurotransmitters and that can alter the cellular properties of neurons or sensory cells that transduce information from the outside world into the electrical code used by neurons. The final section reviews our rapidly expanding knowledge of the molecular factors that induce
an undifferentiated cell to become a neuron, and then guide it to form appropriate synaptic connections with its partners. This section also focuses on the role of ongoing experience and activity in shaping these connections, and finishes with an account of mechanisms thought to underlie the
phenomena of learning and memory.
New for the Third Edition: This is a thoroughly revised and expanded edition (60 pages longer) and features a new 8-page, 4-color insert as well as the following changes:
1. The mapping of the human genome and that of other species has led to the discovery of numerous new proteins that regulate the excitability, development, and function of neurons. These have been incorporated into the new edition in nearly all of the chapters. 2. The first section of the book,
which dealswith neuronal excitability, has been reorganized to make it more readable for those students with less background in physical sciences. A new chapter has been added to this section to allow the incorporation of new information on ion channel structure and on the role of cha

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